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CD11c (Integrin αX) Mouse anti-Human, RB545, Clone: B-ly6, BD Horizon™

Catalog No. BDB569252 Shop All BD Biosciences Products
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BDB569252 25 Tests
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Catalog No. BDB569252 Supplier BD Biosciences Supplier No. 569252
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Description

Mouse Monoclonal Antibody

The B-ly6 monoclonal antibody specifically binds to the 150 kDa adhesion glycoprotein CD11c (p150, integrin α chain). CD11c is expressed on dendritic cells, monocytes, macrophages, granulocytes, NK cells and subsets of B and T cells. It associates with CD18 to form the CD11c/CD18 complex that binds fibrinogen and has been reported to be a receptor for iC3b and ICAM-1. Reports indicate that CD11c/CD18 plays a role as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium.

CD11c (Integrin αX) Monoclonal antibody specifically detects CD11c (Integrin αX) in Human samples. It is validated for Flow Cytometry
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11c (Integrin αX)
Applications Flow Cytometry
Classification Monoclonal
Clone B-ly6
Conjugate RB545
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6
Host Species Mouse
Immunogen Spleen Cells from Human with Hairy Cell Leukemia
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3687
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Form Purified
Isotype IgG1 κ
Excitation/Emission Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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