CD11c (Integrin αX) Mouse anti-Human, RB545, Clone: B-ly6, BD Horizon™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 569252

Catalog No. BDB569252

Description

The B-ly6 monoclonal antibody specifically binds to the 150 kDa adhesion glycoprotein CD11c (p150, integrin α chain). CD11c is expressed on dendritic cells, monocytes, macrophages, granulocytes, NK cells and subsets of B and T cells. It associates with CD18 to form the CD11c/CD18 complex that binds fibrinogen and has been reported to be a receptor for iC3b and ICAM-1. Reports indicate that CD11c/CD18 plays a role as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium.

CD11c (Integrin αX) Monoclonal antibody specifically detects CD11c (Integrin αX) in Human samples. It is validated for Flow Cytometry

Specifications

• Antigen: CD11c (Integrin αX)
• Classification: Monoclonal
• Conjugate: RB545
• Gene Alias: ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6
• Immunogen: Spleen Cells from Human with Hairy Cell Leukemia
• Quantity: 25 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Form: Purified
• Excitation/Emission: Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

• Applications: Flow Cytometry
• Clone: B-ly6
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 3687
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
• Isotype: IgG1 κ