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CD122 Mouse anti-Human, Brilliant Violet 421, Clone: Mik-β2, BD Optibuild™

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BDB743187 50 μg
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Catalog No. BDB743187 Supplier BD Biosciences Supplier No. 743187
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Description

Mouse Monoclonal Antibody

The Mik-β2monoclonal antibody specifically recognizes the 75 kDβsubunit (p75) of the IL-2 receptor (IL-2Rβ). Cell surface IL-2Rβmolecules are expressed by T cells, B cells, monocytes, myeloid precursors, NK cells, and LGL. Together with theαsubunit (p55, CD25) and the commonγsubunit (CD132;γc subunit of the IL-2R, IL-4R, and IL-7R), the IL-2Rβmolecule forms a high-affinity, signaling receptor complex for IL-2 which can be expressed by activated T and B lymphocytes. Alternatively, some cell types, such as NK cells and myeloid cell populations, coexpress IL-2Rβmolecules andγc subunits to form intermediate-affinity, signalling receptor complexes for IL-2.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates. BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences. Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates. Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD122
Classification Monoclonal
Clone Mik-β2
Concentration 0.2mg/mL
Conjugate Brilliant Violet 421
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias IL-2 Receptor β chain, IL2RB, IL-2Rβ, IL15RB, P70-75
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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