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Invitrogen™ CD122 Polyclonal Antibody
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Catalog No. PIPA547622
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100 μg
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PIPA547622 100 μg
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Catalog No. PIPA547622 Supplier Invitrogen™ Supplier No. PA547622
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Description

Sheep Polyclonal Antibody

In direct ELISAs and Western blots, approximately 30% cross-reactivity with recombinant human IL-20 R beta is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD122
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Il2rb
Gene Accession No. P16297
Gene Alias CD122; CD122 antigen; high affinity IL-2 receptor beta subunit; high affinity IL-2 receptor subunit beta; IL-15 receptor beta chain; IL15RB; IL15Rbeta; IL-15Rbeta; IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; Il-2/15Rbeta; IL-2R subunit beta; IL2RB; IL-2RB; IL2RBC; Il-2Rbeta; interleukin 15 receptor, beta; interleukin 2 receptor subunit beta; interleukin 2 receptor, beta; interleukin 2 receptor, beta chain; Interleukin-15 receptor subunit beta; Interleukin-2 receptor subunit beta; p70; p70-75; p75
Gene Symbols Il2rb
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse IL-20 R beta Asp14-Asn215.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16185
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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