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CD123 Mouse, anti-Human, R718, Clone: 9F5, BD OptiBuild™

Catalog No. BDB752032 Shop All BD Biosciences Products
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BDB752032 50 μg
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Catalog No. BDB752032 Supplier BD Biosciences Supplier No. 752032
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Description

Mouse Monoclonal Antibody

The 9F5 monoclonal antibody specifically binds to CD123. CD123 is the 70 kDa IL-3 receptor α chain (IL-3Rα) that associates with the 120-140 kDa β subunit (CD131/Common β-chain/βc) to form the functional IL-3 receptor complex. The βc chain is also shared with distinct α chain subunits to form the functional heterodimeric receptors for interleukins IL-5 and GM-CSF. IL-3Rα is expressed on a subset of peripheral blood dendritic cells, myeloid precursors, basophils, mast cells, macrophages, and megakaryocytes. Reports indicate that IL-3Rα is also expressed on lymphocytes. The IL-3R plays an important role in hematopoietic progenitor cell growth and differentiation. This antibody does not block binding of IL-3 to the IL-3 receptor.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD123
Applications Flow Cytometry
Classification Monoclonal
Clone 9F5
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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