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Invitrogen™ CD123 Polyclonal Antibody
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Catalog No. PIPA585146
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100 μL
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PIPA585146 100 μL
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Catalog No. PIPA585146 Supplier Invitrogen™ Supplier No. PA585146
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Positive Control: THP-1, IL3 Receptor alpha-transfected (+) 293T whole cell extracts. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD123
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene IL3RA
Gene Accession No. P26951
Gene Alias CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1
Gene Symbols IL3RA
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human IL3 Receptor alpha. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3563
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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