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Invitrogen™ CD124 Recombinant Rabbit Monoclonal Antibody (Astra-1), Alexa Fluor™ 647, eBioscience™

Catalog No. 51124182
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51-124-182 100 μg
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Catalog No. 51-124-182 Supplier Invitrogen™ Supplier No. 51124182
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Description

Rabbit Recombinant Monoclonal Antibody

Description: This Astra-1 recombinant rabbit monoclonal antibody reacts with mouse CD124, which is also known as the IL4 receptor alpha (IL4RA) chain. Applications Tested: This Astra-1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This may be used at less than or equal to 0.06 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser Filtration: 0.2 μm post-manufacturing filtered.

IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD124
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone Astra-1
Concentration 0.2 mg/mL
Conjugate Alexa Fluor 647
Formulation PBS, proprietary buffer with 0.09% sodium azide; pH 7.2-7.4
Gene Il4ra
Gene Accession No. P16382
Gene Alias 582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha
Gene Symbols Il4ra
Host Species Rabbit
Immunogen Protein corresponding to mouse CD124 (aa26-aa233).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16190
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
Product Line eBioscience
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Safety and Handling

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