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CD127 Monoclonal Antibody (eBioRDR5), eFluor™ 660, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$419.00
Specifications
| Antigen | CD127 |
|---|---|
| Clone | eBioRDR5 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | eFluor 660 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-127-842
|
Invitrogen™
50127842 |
100 Tests |
Each of 1 for $419.00
|
|
|||||
Description
Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules.
CD127 (Interleukin-7, IL-7) is a glycoprotein involved in the regulation of lymphopoiesis. The response of cells to CD127 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. CD127 consists of an alpha chain and a gamma chain. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. CD127 promotes the proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells. The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. Diseases associated with CD127 dysfunction include severe combined immunodeficiency and T cell negative/B cell negative/NK positive severe combined immunodeficiency.Specifications
| CD127 | |
| Flow Cytometry | |
| eFluor 660 | |
| Mouse | |
| Human | |
| 3575 | |
| Primary | |
| Antibody |
| eBioRDR5 | |
| Monoclonal | |
| Liquid | |
| RUO | |
| P16871 | |
| IgG1 κ | |
| Affinity chromatography |
For Research Use Only.
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