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CD13 Monoclonal Antibody (OTI2E4), TrueMAB™, OriGene
SDP

Catalog No. 501681531
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100 μL
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50-168-1531 100 μL
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Catalog No. 50-168-1531 Supplier OriGene Supplier No. TA807395
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Description

Mouse Monoclonal Antibody

CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.

Specifications

Antigen CD13
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone OTI2E4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene ANPEP
Gene Accession No. P15144
Gene Alias APN, CD13, GP150, LAP1, P150, PEPN
Gene Symbols ANPEP
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 668-967 of human ANPEP produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 290
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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