CD13 Mouse anti-Human, Clone: OTI2F10, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF807396

Catalog No. 50-166-8254

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.

Specifications

• Antigen: CD13
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ANPEP
• Gene Alias: APN, CD13, GP150, LAP1, P150, PEPN
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2F10
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P15144
• Gene Symbols: ANPEP
• Immunogen: Human recombit protein fragment corresponding to amino acids 668-967 of human ANPEP produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a