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  6. Invitrogen™ CD130 (GP130) Recombinant Rabbit Monoclonal Antibody (BLR114H)

Invitrogen™ CD130 (GP130) Recombinant Rabbit Monoclonal Antibody (BLR114H)
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Catalog No. PIMA544419
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100 μL
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PIMA544419 100 μL
PIMA544420 10 μL
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Catalog No. PIMA544419 Supplier Invitrogen™ Supplier No. MA544419
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Description

Rabbit Recombinant Monoclonal Antibody

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD130 (GP130)
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone BLR114H
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation BBS with 0.09% sodium azide; pH 8.2
Gene IL6ST
Gene Accession No. P40189
Gene Alias 5133400A03Rik; AA389424; Ac1055; BB405851; CD130; CD130 antigen; CDW130; D13Ertd699e; EGK_16499; Gp130; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; GP130-RAPS; IL-6; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6RB; IL-6R-beta; IL6R-beta; IL6ST; interleukin 6 signal transducer; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin 6 signal transducer receptor; interleukin receptor beta chain; interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; interleukin-6 signal transducer receptor; membrane glycoprotein; membrane glycoprotein 130; membrane glycoprotein gp130; oncostatin-M receptor subunit alpha
Gene Symbols IL6ST
Host Species Rabbit
Immunogen Recombinant protein representing the extracellular domain of Human GP130/CD130 (interleukin-6 receptor subunit beta, residues 23-323).
Purification Method Purified
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3572
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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