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  6. CD132 Mouse anti-Human, PE, Clone: AG184, BD

CD132 Mouse anti-Human, PE, Clone: AG184, BD

Catalog No. BDB555900 Shop All BD Biosciences Products
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0.2 mg
25 μg
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BDB555900 0.2 mg
BDB561699 25 μg
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Catalog No. BDB555900 Supplier BD Biosciences Supplier No. 555900
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Description

Mouse Monoclonal Antibody

TheAG184 monoclonal antibody specifically binds to the 65-70 kDa common γ subunit (γc) that is shared by the IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21 receptor complexes. The γc receptor is a type 1 transmembrane glycoprotein that is constitutively expressed by most peripheral T and B lymphocytes, NK cells, monocytes and granulocytes. The cytoplasmic domain of the γc chain plays an important role in cytokine-mediated signal transduction. By immunofluorescent staining and flow cytometric analyses, the AG184 antibody has been shown to specifically recognize human γc expressed by cell lines including human γc gene-transfected cell lines which are known to express the human γc chain. The AG184 antibody can bind the γc chain in the receptors complexed with IL-2, IL-4, or IL-7, indicating that the antibody recognizes an epitope which is distinct from the cytokine binding site of the γc chain.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD132
Applications Flow Cytometry
Classification Monoclonal
Clone AG184
Concentration 0.2mg/mL
Conjugate PE
Description IL2RG; IL-2RG; IL-2Rγ; Common gamma chain; γc; CIDX; SCIDX; SCIDX1; IMD4
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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