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Invitrogen™ CD137 (4-1BB) Monoclonal Antibody (2G1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA542580

Catalog No. PIMA542580


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Description

Description

Positive Control: A431, A549, LOVO, rat brain tissue, rat hippocampus tissue, human liver cancer tissue, mouse brain tissue, human tonsil tissue, Jurkat. Subcellular Location: Membrane. Extracellular space.

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD137 (4-1BB)
Monoclonal
2 mg/mL
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
P20334, Q07011
TNFRSF9
Recombinant full length protein.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG1
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
2G1
Unconjugated
TNFRSF9
4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9
Mouse
Protein A
RUO
21942, 3604, 500590
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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