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  6. Invitrogen™ CD137 (4-1BB) Monoclonal Antibody (4B4 (4B4-1)), Alexa Fluor™ 700, eBioscience™, Invitrogen™ 

Invitrogen™ CD137 (4-1BB) Monoclonal Antibody (4B4 (4B4-1)), Alexa Fluor™ 700, eBioscience™, Invitrogen™

Catalog No. 56137941
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56-137-941 25 Tests
56-137-942 100 Tests
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Catalog No. 56-137-941 Supplier Invitrogen™ Supplier No. 56137941
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Description

Mouse Monoclonal Antibody

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD137 (4-1BB)
Applications Flow Cytometry
Classification Monoclonal
Clone 4B4 (4B4-1)
Concentration 5 μL/Test
Conjugate Alexa Fluor 700
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene TNFRSF9
Gene Accession No. Q07011
Gene Alias 4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9
Gene Symbols TNFRSF9
Host Species Mouse
Purification Method Affinity chromatography
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3604
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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