Invitrogen™ CD137 Recombinant Human Monoclonal Antibody (1H7)

Human Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA549969

Catalog No. FEMA549969

Description

CD137 Recombinant Monoclonal Antibody for ELISA

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.

Specifications

• Antigen: CD137
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Gene Accession No.: Q07011
• Gene Symbols: TNFRSF9
• Immunogen: Recombinant Human TNFRSF9 protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2

• Applications: ELISA, Neutralization
• Clone: 1H7
• Conjugate: Unconjugated
• Gene: TNFRSF9
• Gene Alias: 4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9
• Host Species: Human
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3604
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid