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Invitrogen™ CD138 Monoclonal Antibody (B-A38), PE
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Catalog No. PIMA181808
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100 Tests
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Catalog No. Quantity
PIMA181808 100 Tests
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Catalog No. PIMA181808 Supplier Invitrogen™ Supplier No. MA181808
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Description

Mouse Monoclonal Antibody

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Mouse anti human CD138 antibody, clone B-A38 recognizes human CD138, also known as Syndecan-1 (SDC-1).

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
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Specifications

Antigen CD138
Applications Flow Cytometry
Classification Monoclonal
Clone B-A38
Concentration Conc. Not Determined
Conjugate PE
Formulation PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Sdc1
Gene Accession No. P18827
Gene Alias AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin
Gene Symbols Sdc1
Host Species Mouse
Immunogen U266 cell line.
Purification Method Ion-exchange chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6382
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Lyophilized
Isotype IgG1
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