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Invitrogen™ CD138 (Syndecan-1) Monoclonal Antibody (C3), Invitrogen™
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA543910
This item is not returnable.
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Description
CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
Specifications
CD138 (Syndecan-1) | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
P18827 | |
Sdc1 | |
Gln23-Leu253 (Accession P18827), with N-terminal His and GST Tag. | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
Western Blot | |
C3 | |
Unconjugated | |
Sdc1 | |
AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin | |
Mouse | |
Protein A/G | |
RUO | |
6382 | |
-20°C | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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