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CD138 (Syndecan-1) Monoclonal Antibody (MI15), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$377.00
Specifications
| Antigen | CD138 (Syndecan-1) |
|---|---|
| Clone | MI15 |
| Concentration | 5 μL/Test |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
17-138-842
|
Invitrogen™
17138842 |
100 Tests |
Each of 1 for $377.00
|
|
|||||
Description
Description: This MI15 monoclonal antibody reacts with human CD138, also known as syndecan-1. CD138 is a transmembrane protein containing chondroitin sulfate and heparin sulfate moieties responsible for binding to the extracellular matrix components. CD138 is not expressed by mature B cells but is present on pre-B cells and the finally differentiated plasma cells. Applications Reported: This MI15 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MI15 antibody has been pre-diluted and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.Specifications
| CD138 (Syndecan-1) | |
| 5 μL/Test | |
| Monoclonal | |
| Liquid | |
| RUO | |
| P18827 | |
| U-266 cell line. | |
| Primary |
| MI15 | |
| Flow Cytometry | |
| APC | |
| Mouse | |
| Human | |
| 6382 | |
| IgG1 κ | |
| Antibody |
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