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CD141 Rat anti-Mouse, PE, Clone: LS17-9, BD

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BDB566338 50 μg
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Catalog No. BDB566338 Supplier BD Biosciences Supplier No. 566338
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Description

Rat Monoclonal Antibody

The LS17-9 monoclonal antibody specifically binds to CD141, also known as thrombomodulin (TM or TRBM) or fetomodulin. CD141 is encoded by Thbd /and expressed as a type I transmembrane glycoprotein with an N-terminal C-type lectin domain followed by EGF-like repeats. CD141 is expressed on a variety of cells including endothelial cells, epithelial cells, mesothelial cells, keratinocytes, synovial lining cells, fibroblastic reticular cells, megakaryocytes, dendritic cells, monocytes, macrophages, neutrophils, precursor B cells, and hematopoietic progenitor cells. CD141 is required for normal fetal development. CD141 binds thrombin and this complex can activate Protein C and Thrombin activatable fibrinolysis inhibitor (TAFI), leading to anticoagulant and antifibrinolytic pathway activities

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD141
Classification Monoclonal
Clone LS17-9
Concentration 0.2mg/mL
Conjugate PE
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias Thbd, TM, TRBM, thrombomodulin, fetomodulin, BCDA-3
Host Species Rat
Immunogen Mouse LyEnd.5 Cell Membranes
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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