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CD142 Mouse, anti-Human, R718, Clone: HTF-1, BD OptiBuild™

Catalog No. BDB752248 Shop All BD Biosciences Products
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BDB752248 50 μg
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Catalog No. BDB752248 Supplier BD Biosciences Supplier No. 752248
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Description

Mouse Monoclonal Antibody

The HTF-1 monoclonal antibody specifically binds to CD142. CD142 is a 45-47 kDa, single chain, type I transmembrane glycoprotein also known as Tissue Factor (TF). CD142 has been referred in the literature as coagulation Factor III or thromboplastin and it is expressed on activated endothelial cells and lipopolysaccharide (LPS)-stimulated monocytes/macrophages. TF associates with factor VIIa to form a complex and acts as an enzyme that initiates the blood coagulation cascade. It is known as the major initiator of clotting in normal hemostasis. CD142 can be induced by various inflammatory mediators in monocytes and vascular endothelial cells. This antibody is useful in inflammation, thrombosis and hemostasis research.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD142
Applications Flow Cytometry
Classification Monoclonal
Clone HTF-1
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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