Invitrogen™ CD142 Polyclonal Antibody

Catalog No.	Quantity
PIPA143058	1 mg

Catalog No. PIPA143058

Supplier: Invitrogen™ PA143058

Description

Sheep Polyclonal Antibody

PA1-43058 detects Tissue Factor in human samples. PA1-43058 has successfully been used in Western blot and ELISA applications. PA1-43058 was derived from human tissue factor.

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.

Specifications

• Antigen: CD142
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 13.0 mg/mL
• Conjugate: Unconjugated
• Formulation: 50% water with 50% glycerol and no preservative
• Gene: F3
• Gene Accession No.: P13726
• Gene Alias: AA409063; CD142; Cf3; Cf-3; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); coagulation factor III, tissue factor; F3; TF; TFA; Thromboplastin; Tissue factor
• Gene Symbols: F3
• Host Species: Sheep
• Immunogen: Human Tissue Factor.
• Purification Method: SDS-PAGE
• Quantity: 1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2152
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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