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CD15 Monoclonal Antibody (MCS-1), FITC, Invitrogen™

Catalog No. 01674032
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50 Tests
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Catalog No. Quantity
01-674-032 50 Tests
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Catalog No. 01-674-032 Supplier Thermo Scientific Supplier No. MA112651

Description

Mouse Monoclonal Antibody

This monoclonal anti-CD15 antibody is an IgG3 fraction which will not agglutinate cells, as opposed to most other IgM antibodies which cause cells to aggregate in the cytometer.

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD15
Applications Flow Cytometry
Classification Monoclonal
Clone MCS-1
Conjugate FITC
Formulation PBS with 0.09% sodium azide
Gene FUT4
Gene Accession No. P22083
Gene Alias FUTIV, Lewis X, SSEA-1
Gene Symbols FUT4
Host Species Mouse
Immunogen White blood cells.
Purification Method Affinity chromatography
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2526
Target Species Human
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG3
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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