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CD150 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984916
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100 μL
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50-198-4916 100 μL
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Catalog No. 50-198-4916 Supplier Bioss Supplier No. BS2709R
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Description

Rabbit Polyclonal Antibody

CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).

Specifications

Antigen CD150
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Slamf1
Gene Accession No. Q13291
Gene Alias 4933415F16; AA177906; CD150; CD150 antigen; CDw150; ESTM51; IPO-3; RGD1560634; signaling lymphocyte activation molecule; Signaling lymphocytic activation molecule; signaling lymphocytic activation molecule family member 1; SLAM; SLAM family member 1; Slamf1
Gene Symbols Slamf1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CD150.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6504
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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