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Invitrogen™ CD154 (CD40 Ligand) Monoclonal Antibody (MR-1)
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Catalog No. PIMA110108
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100 μg
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PIMA110108 100 μg
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Catalog No. PIMA110108 Supplier Invitrogen™ Supplier No. MA110108
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Armenian Hamster Monoclonal Antibody

This antibody detects an extracellular epitope on murine CD154 / CD40L (CD40-ligand), a 39 kDa cell surface type II glycoprotein expressed predominantly on activated CD4+ lymphocytes. Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test. Functional Application: Blocking.

CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
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Specifications

Antigen CD154 (CD40 Ligand)
Applications Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry
Classification Monoclonal
Clone MR-1
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene CD40LG
Gene Accession No. P27548
Gene Alias CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
Gene Symbols CD40LG
Host Species Armenian Hamster
Immunogen Activated mouse Th1 clone D1.6.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21947
Target Species Mouse
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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