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Invitrogen™ CD155 Monoclonal Antibody (3F1)

Catalog No. PIMA533379
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100 μg
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Catalog No. Quantity
PIMA533379 100 μg
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Catalog No. PIMA533379 Supplier Invitrogen™ Supplier No. MA533379

Description

Rat Monoclonal Antibody

Product is supplied at 1 mL (100 μL/mL). Application Notes: Flow cytometry - This antibody stains the extracellular domain of mouse CD155. The thymocytes were blocked with 5% mouse serum before incubation with clone 3F1 for 1 hour at 4°C As positive control CD4+CD8+ thymocytes was used and as negative control CD155-/- derived cells. Functional Assay- This antibody functions as antagonist. The antibody was functionally tested by blocking adhesion of Sf9 cells expressing mCD155 to RMA, CD4+ and CD8+ cells. Furthermore, antibody clone 3F1 prevents formation of mCD155/ligand complexes. Positive control: CD4+CD8+ mouse thymocytes; Negative control: CD155-/- cells.

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD155
Applications Flow Cytometry, Functional Assay
Classification Monoclonal
Clone 3F1
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and no preservative
Gene PVR
Gene Accession No. 0
Gene Alias 3830421F03Rik; AI325026; AI987993; CD112; CD155; D7Ertd458e; FLJ25946; herpes virus entry mediator B; Herpesvirus entry mediator B; hveB; HVED; mE4; mHveB; Mph; murine herpes virus entry protein B; murine herpesvirus entry protein B; NECL5; necl-5; Nectin cell adhesion molecule 2; Nectin2; Nectin-2; nectin-like 5; nectin-like protein 5; Poliovirus receptor; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity; PVR; Pvrl2; PVS; sCD112; soluble CD112; Taa1; TAGE4; tumor-associated antigen 1; tumor-associated glycoprotein pE4
Gene Symbols PVR
Host Species Rat
Immunogen Ectodomain of recombinant His-tagged CD155.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 52118
Target Species Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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