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Invitrogen™ CD155 Monoclonal Antibody (TX56), APC, eBioscience™
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Catalog No. 5015100
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100 μg
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Catalog No. Quantity
50-151-00 100 μg
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Catalog No. 50-151-00 Supplier Invitrogen™ Supplier No. 17155182
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Description

Rat Monoclonal Antibody

Description: This TX56 monoclonal antibody reacts with mouse CD155 (also known as poliovirus receptor or PVR), a member of the Ig superfamily of nectins and nectin-like proteins. CD155 is expressed on thymocytes (e.g. CD4+CD8+ and CD4+ cells), peripheral T and B lymphocytes (e.g. regulatory T cells, activated T cells, marginal zone B cells, and plasma cells), natural killer (NK) cells, dendritic cells (e.g. mature and activated), and monocytes. CD155 interacts with other nectins, including Nectin-3 and the extraceullar matrix protein vitronectin, the adhesion molecule CD226/DNAM-1, and the NK cell receptor CD96. CD155 plays a role in cell-cell adhesion, including formation of adherens junctions, cell migration, polarization, and NK-mediated cytotoxicity. In humans, but not in mice, CD155 is the receptor for poliovirus. Applications Reported: This TX56 antibody has been reported for use in flow cytometric analysis. Applications Tested: This TX56 antibody has been tested by flow cytometric analysis on mouse thymocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-man...

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD155
Applications Flow Cytometry
Classification Monoclonal
Clone TX56
Concentration 0.2 mg/mL
Conjugate APC
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene PVR
Gene Accession No. 0
Gene Alias 3830421F03Rik; AI325026; AI987993; CD112; CD155; D7Ertd458e; FLJ25946; herpes virus entry mediator B; Herpesvirus entry mediator B; hveB; HVED; mE4; mHveB; Mph; murine herpes virus entry protein B; murine herpesvirus entry protein B; NECL5; necl-5; Nectin cell adhesion molecule 2; Nectin2; Nectin-2; nectin-like 5; nectin-like protein 5; Poliovirus receptor; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity; PVR; Pvrl2; PVS; sCD112; soluble CD112; Taa1; TAGE4; tumor-associated antigen 1; tumor-associated glycoprotein pE4
Gene Symbols PVR
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 52118
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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