Invitrogen™ CD155 Monoclonal Antibody (TX56), APC, eBioscience™

Rat Monoclonal Antibody

Supplier:  Invitrogen™ 17155182

Catalog No. 50-151-00

Description

Description: This TX56 monoclonal antibody reacts with mouse CD155 (also known as poliovirus receptor or PVR), a member of the Ig superfamily of nectins and nectin-like proteins. CD155 is expressed on thymocytes (e.g. CD4+CD8+ and CD4+ cells), peripheral T and B lymphocytes (e.g. regulatory T cells, activated T cells, marginal zone B cells, and plasma cells), natural killer (NK) cells, dendritic cells (e.g. mature and activated), and monocytes. CD155 interacts with other nectins, including Nectin-3 and the extraceullar matrix protein vitronectin, the adhesion molecule CD226/DNAM-1, and the NK cell receptor CD96. CD155 plays a role in cell-cell adhesion, including formation of adherens junctions, cell migration, polarization, and NK-mediated cytotoxicity. In humans, but not in mice, CD155 is the receptor for poliovirus. Applications Reported: This TX56 antibody has been reported for use in flow cytometric analysis. Applications Tested: This TX56 antibody has been tested by flow cytometric analysis on mouse thymocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufa...

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CD155
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: 0
• Gene Symbols: PVR
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 52118
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: TX56
• Conjugate: APC
• Gene: PVR
• Gene Alias: 3830421F03Rik; AI325026; AI987993; CD112; CD155; D7Ertd458e; FLJ25946; herpes virus entry mediator B; Herpesvirus entry mediator B; hveB; HVED; mE4; mHveB; Mph; murine herpes virus entry protein B; murine herpesvirus entry protein B; NECL5; necl-5; Nectin cell adhesion molecule 2; Nectin2; Nectin-2; nectin-like 5; nectin-like protein 5; Poliovirus receptor; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity; PVR; Pvrl2; PVS; sCD112; soluble CD112; Taa1; TAGE4; tumor-associated antigen 1; tumor-associated glycoprotein pE4
• Host Species: Rat
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov