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CD158 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984868
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50-198-4868 100 μL
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Catalog No. 50-198-4868 Supplier Bioss Supplier No. BS2643R
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Description

Rabbit Polyclonal Antibody

CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.

Specifications

Antigen CD158
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene KIR2DL4
Gene Accession No. Q99706
Gene Alias CD158 antigen-like family member D; CD158D; G9P; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4; Killer cell immunoglobulin-like receptor 2DL4; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4; Killer cell inhibitory receptor 103AS; killer Ig receptor; killer-cell immunoglobulin-like receptor; killer-cell immunoglobulin-like receptor 2DL4; KIR; KIR103; KIR103AS; KIR-103AS; KIR2DL4; KIR-2DL4; MHC class I NK cell receptor KIR103AS; natural killer cell inhibitory receptor; NK cell receptor
Gene Symbols KIR2DL4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CD158 .
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3805
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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