Epredia™ Lab Vision™ CD16/Fcγ Receptor III, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ CD16/Fcγ Receptor III, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS1085S1

Catalog No. MS1085S1

Description

CD16 (also known low affinity Fc γ receptor III for IgG (FcγRIII) or Leu 11) exists as a polypepetide-anchored from (FCγRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcγRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2. CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity.

Host Species: Mouse

Clone: 2H7

Isotype: IgG2a

Species Reactivity: Human. Others not tested.

Epitope: Extracellular

Immunogen: Recombinant protein encoding the external domain of human CD16

Molecular Weight: 50-65 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin only)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: CD16 Ab-2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant protein encoding the external domain of human CD16
• Quantity: 500 μL
• Research Discipline: Signal Transduction
• Target Species: Human
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin)
• Clone: 2H7
• Host Species: Mouse
• Purification Method: Tonsil
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated