Invitrogen™ CD160 Monoclonal Antibody (BY55), PE, eBioscience™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 12160942

Catalog No. 12-160-942

Description

Description: This BY55 monoclonal antibody reacts with human CD160, a member of the immunoglobulin superfamily expressed on natural killer cells, natural killer T cells, activated and/or memory CD4 and CD8 T cells, gamma delta T cells, and intraepithelial cells. CD160 has been reported to bind herpes virus entry mediator (HVEM) in a complex with LIGHT and BTLA to deliver an inhibitory signal to CD4 T cells that abrogates proliferation and cytokine production. Three alternative splice variants of CD160 have also been identified in natural killer cells. Applications Reported: This BY55 antibody has been reported for use in flow cytometric analysis. Applications Tested: This BY55 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. It is involved in cell proliferation, cell surface receptor signaling pathways, cellular defense response, and regulation of immune response.

Specifications

• Antigen: CD160
• Classification: Monoclonal
• Concentration: 5 μL/Test
• Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
• Gene Accession No.: O95971
• Gene Symbols: CD160
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11126
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: BY55
• Conjugate: PE
• Gene: CD160
• Gene Alias: AU045688; BY55; CD160; CD160 antigen; CD160 antigen, soluble form; CD160 molecule; CD160 transmembrane isoform; CD160-delta Ig; natural killer cell BY55; natural killer cell receptor; natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member; NK1; NK28; RGD1563598
• Host Species: Mouse
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM