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Invitrogen™ CD162 Monoclonal Antibody (TC2), PE
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Catalog No. PIMA110117
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100 Tests
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Catalog No. Quantity
PIMA110117 100 Tests
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Catalog No. PIMA110117 Supplier Invitrogen™ Supplier No. MA110117
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Description

Mouse Monoclonal Antibody

This antibody reacts with an extracellular epitope of CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes; it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.

CD162 (PSGL-1) is a 120 kDa homodimer protein found on the surface of leukocytes and platelets. CD162 is known to bind CD62P (P-selectin), CD62L (L-selectin), and to a lower degree CD62E (E-selectin). These interactions play a critical role in leukocyte adhesion, rolling and extravasation. CD162 has been shown to be an important immune marker of T cell exhaustion in chronic viral infections and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD162
Applications Flow Cytometry
Classification Monoclonal
Clone TC2
Conjugate PE
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene SELPLG
Gene Accession No. Q14242
Gene Alias CD162; CLA; Cutaneous lymphocyte associated antigen; cutaneous lymphocyte-associated associated antigen; leukocyte cell surface adhesion molecule; P-selectin glycoprotein ligand 1; P-selectin glycoprotein ligand 1 propeptide; P-selectin glycoprotein ligand-1; Psgl1; Psgl-1; Selectin P ligand; selectin, platelet (p-selectin) ligand; Selp1; SELPG; Selpl; SELPLG
Gene Symbols SELPLG
Host Species Mouse
Immunogen Human thymocytes.
Purification Method Size-exclusion chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6404
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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