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CD162 Mouse, anti-Human, R718, Clone: KPL-1, BD OptiBuild™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 751873

Catalog No. BDB751873


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Description

Description

The KPL-1 monoclonal antibody specifically binds to p-selectin glycoprotein ligand-1 (PSGL-1), a 120-220 kDa, mucin-like type I transmembrane glycoprotein. CD162 is expressed on neutrophils, monocytes, and most lymphocytes. CD162 binds to CD62P (P-Selectin), CD62E (E-Selectin) and CD62L (L-Selectin). This molecule mediates rolling of leukocytes on activated endothelium and the interaction between leukocytes and activated platelets or other leukocytes found at inflammatory sites. It has also been reported that this clone completely inhibits the interaction between P-Selectin and either CD4-T cells or neutrophils.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD162
Monoclonal
R718
50 μg
Primary
Refrigerate Upon Arrival
Flow Cytometry
KPL-1
Mouse
RUO
Human
Liquid
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