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CD162 Mouse, anti-Human, R718, Clone: KPL-1, BD OptiBuild™
Mouse Monoclonal Antibody
Supplier: BD Biosciences 751873
Description
The KPL-1 monoclonal antibody specifically binds to p-selectin glycoprotein ligand-1 (PSGL-1), a 120-220 kDa, mucin-like type I transmembrane glycoprotein. CD162 is expressed on neutrophils, monocytes, and most lymphocytes. CD162 binds to CD62P (P-Selectin), CD62E (E-Selectin) and CD62L (L-Selectin). This molecule mediates rolling of leukocytes on activated endothelium and the interaction between leukocytes and activated platelets or other leukocytes found at inflammatory sites. It has also been reported that this clone completely inhibits the interaction between P-Selectin and either CD4-T cells or neutrophils.

Specifications
CD162 | |
Monoclonal | |
R718 | |
50 μg | |
Primary | |
Refrigerate Upon Arrival |
Flow Cytometry | |
KPL-1 | |
Mouse | |
RUO | |
Human | |
Liquid |
Safety and Handling
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