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Invitrogen™ CD169 (Siglec-1) Monoclonal Antibody (MOMA-1), FITC
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Catalog No. PIMA528189
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100 μg
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Catalog No. Quantity
PIMA528189 100 μg
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Catalog No. PIMA528189 Supplier Invitrogen™ Supplier No. MA528189
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Description

Rat Monoclonal Antibody

Rat anti Mouse CD169, clone MOMA-1 recognizes murine CD169, also known as sialoadhesin or Siglec-1. CD169 is a lectin-like receptor expressed by certain populations of macrophages including marginal zone metallophils of the spleen, subcapsular macrophages of lymph nodes and stromal macrophages in bone marrow (Morris et al. 1991).

The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.
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Specifications

Antigen CD169 (Siglec-1)
Applications Immunohistochemistry (Frozen), Immunocytochemistry
Classification Monoclonal
Clone MOMA-1
Concentration 0.1 mg/mL
Conjugate FITC
Formulation PBS with 1% BSA and 0.09% sodium azide
Gene SIGLEC1
Gene Accession No. Q62230
Gene Alias Cd169; dJ1009E24.1; macrophage receptor; p210; pSn; SA; SER; sheep erythrocyte receptor; sialic acid binding Ig like lectin 1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC1; Siglec-1; SN
Gene Symbols SIGLEC1
Host Species Rat
Immunogen Stromal (reticular) elements from mouse lymph nodes.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20612
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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