Invitrogen™ CD17 Monoclonal Antibody (MEM-68)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA110118

Catalog No. PIMA110118

Description

This antibody recognizes CD17, an extracellular membrane lipid moiety lactosylceramide expressed on granulocytes, monocytes and platelets.

CD17, lactosylceramide, is an ubiquitous glycosphingolipid with uncharged disaccharide headgroup, highly enriched in lipid raft-derived structures. Besides playing a pivotal role in the biosynthesis of complex glycosphingilipids, lactosylceramide is involved in cell-cell and cell-matrix interactions and in signaling events linked to cell differentiation, development, apoptosis and oncogenesis. Lactosylceramide regulates integrin functions and production of nitric oxide. Its expression defines successive stages in the maturation of myeloid cells.

Specifications

• Antigen: CD17
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 15mM sodium azide; pH 8
• Host Species: Mouse
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM

• Applications: Flow Cytometry
• Clone: MEM-68
• Conjugate: Unconjugated
• Gene Alias: Lactosylceramide
• Immunogen: Pre-B cell line NALM-6.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: 4°C, do not freeze
• Form: Liquid