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Invitrogen™ CD17 Monoclonal Antibody (MEM-68)
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Catalog No. PIMA110118
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100 μg
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Catalog No. Quantity
PIMA110118 100 μg
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Catalog No. PIMA110118 Supplier Invitrogen™ Supplier No. MA110118
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Description

Mouse Monoclonal Antibody

This antibody recognizes CD17, an extracellular membrane lipid moiety lactosylceramide expressed on granulocytes, monocytes and platelets.

CD17, lactosylceramide, is an ubiquitous glycosphingolipid with uncharged disaccharide headgroup, highly enriched in lipid raft-derived structures. Besides playing a pivotal role in the biosynthesis of complex glycosphingilipids, lactosylceramide is involved in cell-cell and cell-matrix interactions and in signaling events linked to cell differentiation, development, apoptosis and oncogenesis. Lactosylceramide regulates integrin functions and production of nitric oxide. Its expression defines successive stages in the maturation of myeloid cells.
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Specifications

Antigen CD17
Applications Flow Cytometry
Classification Monoclonal
Clone MEM-68
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 15mM sodium azide; pH 8
Gene Alias Lactosylceramide
Host Species Mouse
Immunogen Pre-B cell line NALM-6.
Purification Method Sequential chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgM
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