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CD171 Monoclonal Antibody (UJ127), Biotin, Invitrogen™

Catalog No. PIMA514137
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500 μL
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PIMA514137 500 μL
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Catalog No. PIMA514137 Supplier Thermo Scientific Supplier No. MA514137
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Description

Mouse Monoclonal Antibody

MA5-14137 targets L1 Cell Adhesion Molecule in IHC (P), IP, and WB applications and shows reactivity with Human samples. The MA5-14137 immunogen is homogenous suspension of 16 week human fetal brain.

L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD171
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone UJ127
Concentration 0.2 mg/mL
Conjugate Biotin
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene L1CAM
Gene Accession No. P32004
Gene Alias antigen identified by monoclonal antibody R1; CAML1; CD 171; CD171; CD171 molecule; HSAS; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1CAM; MASA; MIC5; N-CAM L1; NCAML1; N-CAML1; N-CAM-L1; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; neural cell adhesion molecule L1; NILE; S10; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM; SPG1
Gene Symbols L1CAM
Host Species Mouse
Immunogen Homogenous suspension of 16 week human fetal brain
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3897
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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