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Invitrogen™ CD171 Polyclonal Antibody
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Catalog No. PIPA599660
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100 μL
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PIPA599660 100 μL
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Catalog No. PIPA599660 Supplier Invitrogen™ Supplier No. PA599660
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CD171/N-CAML1.

L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD171
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene L1CAM
Gene Accession No. P32004
Gene Alias antigen identified by monoclonal antibody R1; CAML1; CD 171; CD171; CD171 molecule; HSAS; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1CAM; MASA; MIC5; N-CAM L1; NCAML1; N-CAML1; N-CAM-L1; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; neural cell adhesion molecule L1; NILE; S10; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM; SPG1
Gene Symbols L1CAM
Host Species Rabbit
Immunogen A synthesized peptide derived from human L1CAM(Accession P32004), corresponding to amino acid residues E1157-S1207.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3897
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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