Invitrogen™ CD179b Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595623

Catalog No. PIPA595623

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human placenta tissue. IHC: human B lymphocytic tumor tissue, human tonsil tissue, human tonsil tissue, mouse spleen tissue, rat spleen tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The preB cell receptor, CD179b, is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation and differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CD179b
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IGLL1
• Gene Alias: 14.1; AGM2; BB139905; CD179 antigen-like family member B; CD179b; CD179b antigen; ig lambda-5; IGL1; IGL5; Igl-5; IGLJ IGLL; IGLJ14.1; Igll; Igll1; IGO; IGVPB; immunoglobulin lambda chain 5; immunoglobulin lambda like polypeptide 1; immunoglobulin lambda-like polypeptide 1; immunoglobulin lambda-like polypeptide 5; Immunoglobulin omega polypeptide; immunoglobulin omega polypeptide chain; immunoglobulin-related 14.1 protein; immunoglobulin-related protein 14.1; lambda 5; lambda5; Pre-B lymphocyte-specific protein-2; VPREB2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100360919, 16136, 3543
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P15814, P20764
• Gene Symbols: IGLL1
• Immunogen: E.coli-derived human IGLL1 recombinant protein (L38-S213).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG