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Invitrogen™ CD179b Recombinant Rabbit Monoclonal Antibody (8H16L35)

Catalog No. 702901
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70-290-1 100 μg
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Catalog No. 70-290-1 Supplier Invitrogen™ Supplier No. 702901
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Cat, Pig, Rat. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The preB cell receptor, CD179b, is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation and differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD179b
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 8H16L35
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene IGLL1
Gene Accession No. P15814
Gene Alias 14.1; AGM2; BB139905; CD179 antigen-like family member B; CD179b; CD179b antigen; ig lambda-5; IGL1; IGL5; Igl-5; IGLJ IGLL; IGLJ14.1; Igll; Igll1; IGO; IGVPB; immunoglobulin lambda chain 5; immunoglobulin lambda like polypeptide 1; immunoglobulin lambda-like polypeptide 1; immunoglobulin lambda-like polypeptide 5; Immunoglobulin omega polypeptide; immunoglobulin omega polypeptide chain; immunoglobulin-related 14.1 protein; immunoglobulin-related protein 14.1; lambda 5; lambda5; Pre-B lymphocyte-specific protein-2; VPREB2
Gene Symbols IGLL1
Host Species Rabbit
Immunogen Peptides corresponding to human CD179b [1) aa93-aa112 2) aa152-aa167].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3543
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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