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Description
The 6.7 monoclonal antibody specifically binds to β2 integrin, a 90-95 kDa transmembrane protein, which associates non-covalently as a heterodimer with the a chains of CD11a, CD11b, or CD11c. CD18 is expressed on lymphocytes, monocytes, and more weakly on granulocytes. LFA-1 has been shown to play an important role in homotypic and heterotypic cellular adhesion in immune and inflammatory responses.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Specifications
Specifications
| Antigen | CD18 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 6.7 |
| Conjugate | FITC |
| Description | ITGB2; Integrin beta-2; Beta subunit for LFA-1, MAC-1/CR3, and p150,95 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Cloned Human DS6 TCR γδ+ Cells |
| Purification Method | Affinity Purified |
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Safety and Handling
For Research Use Only.
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