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CD197 (CCR7) Monoclonal Antibody (4B12), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
$3260.00
Specifications
Antigen | CD197 (CCR7) |
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Clone | 4B12 |
Concentration | 1 mg/mL |
Classification | Monoclonal |
Conjugate | Functional Grade |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
16-197-138
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Invitrogen™
16197138 |
5 mg |
Each of 1 for $3,260.00
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Description
CCR7 is a member of the G protein coupled receptor family, which is a subfamily of chemokines. CCR7 was identified to be induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. CCR7 is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries. Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.Specifications
CD197 (CCR7) | |
1 mg/mL | |
Functional Grade | |
Rat | |
Mouse | |
P47774 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |
4B12 | |
Monoclonal | |
Liquid | |
RUO | |
PBS with no preservative; pH 7.2 | |
12775 | |
Primary | |
4°C | |
Ccr7 |
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