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CD199 (CCR9) Monoclonal Antibody (eBioCW-1.2 (CW-1.2)), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$196.00 - $460.00
Specifications
Antigen | CD199 (CCR9) |
---|---|
Clone | eBioCW-1.2 (CW-1.2) |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-151-20
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Invitrogen™
17199180 |
25 μg |
Each for $196.00
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50-112-8764
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Invitrogen™
17199182 |
100 μg |
Each for $460.00
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Description
Description: The eBioCW-1.2 monoclonal antibody reacts with mouse CCR9 (CD199), which is the receptor for thymus-expressed chemokine (TECK). CCR9 is a member of the G protein coupled receptor (GPCR) supergene family, and is involved in trafficking of T cell progenitors within the thymus. CCR9 expression during thymocyte development commences at the double-negative (DN) 3 stage (CD4-CD8-CD25+CD44-), peaks in the double-positive (DP) stage (CD4+CD8+CD25-CD44-), and is down-regulated in commited CD4+ or CD8+ single-positive (SP) thymoyctes. CCR9-deficient mice show a mild impairment in thymoycte development. In the periphery, CCR9 is thought to be expressed on naive CD8+ T cells, but not on naive CD4+ T cells. Applications Reported: This eBioCW-1.2 (CW-1.2) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioCW-1.2 (CW-1.2) antibody has been tested by flow cytometric analysis of mouse thymocytes. This can be used at less than or equal to 0.25 μg per million cells in a 100 μL total staining volume. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.
The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.Specifications
CD199 (CCR9) | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
A130091K22Rik; C-C chemokine receptor type 9; C-C CKR-9; C-C motif chemokine receptor 9; CC-CKR-9; Ccr9; CCR-9; CDw199; CDw199 antigen; chemokine (C-C motif) receptor 9; chemokine C-C receptor 10; Cmkbr10; G protein-coupled receptor 28; GPR28; GPR-9-6; G-protein coupled receptor 28 | |
Ccr9 | |
Primary | |
4°C, store in dark, DO NOT FREEZE! | |
Ccr9 |
eBioCW-1.2 (CW-1.2) | |
Flow Cytometry | |
APC | |
Mouse | |
Mouse | |
Q9WUT7 | |
12769 | |
IgG2a | |
Affinity chromatography | |
Antibody |
For Research Use Only.
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