CD1b Antibody (RIV12), FITC, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234714F

Catalog No. NB006385

Description

CD1b Monoclonal specifically detects CD1b in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: CD1b
• Classification: Monoclonal
• Conjugate: FITC
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: CD1B
• Immunogen: Human peripheral lymphocytes (Uniprot: P29016)
• Quantity: 0.1 mL
• Research Discipline: Immunology
• Test Specificity: The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
• Clone: RIV12
• Dilution: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
• Gene Alias: CD1, CD1A, CD1b antigen, CD1B antigen, b polypeptide, CD1b molecule, cortical thymocyte antigen CD1B, differentiation antigen CD1-alpha-3, MGC125990, MGC125991, R1, T-cell surface glycoprotein CD1b
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG1 κ