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Invitrogen™ CD1b Polyclonal Antibody
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Catalog No. PIPA582775
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100 μL
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PIPA582775 100 μL
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Catalog No. PIPA582775 Supplier Invitrogen™ Supplier No. PA582775
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IHGWDSDSGT AIFLKPWSKG NFSDKEVAEL EEIFRVYIFG FAREVQDFAG DFQMKYPFEI QGIAGCELHS GGAIVSFLRG ALGGLDFLSV KNASCVPSPE GGSRAQKFCA LIIQYQGIME TVRILLYETC PRYLLGVLNA GKAD Highest antigen sequence indentity to the following orthologs: Mouse - 37%, Rat - 38%.

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD1b
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CD1B
Gene Accession No. P29016
Gene Alias Antigen-presenting glycoprotein CD1d2; BDCA1; CD1; CD1.2; CD1A; CD1b; CD1B antigen, b polypeptide; CD1b molecule; CD1C antigen; CD1d.2; Cd1d2; CD1d2 antigen; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; Ly-38; MGC125990; MGC125991; R1; RP11-101J8.3; RP11-101J8.4; T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1d2
Gene Symbols CD1B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CD1B. Recombinant protein control fragment (Product #RP-90350).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 910
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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