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Invitrogen™ CD1b Polyclonal Antibody
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Catalog No. PIPA595541
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100 μg
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PIPA595541 100 μg
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Catalog No. PIPA595541 Supplier Invitrogen™ Supplier No. PA595541
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human placenta tissue, human PC-3 whole cell, human SW620 whole cell, human THP-1 whole cell, human MDA-MB-231 whole cell, human K562 whole cell, human A431 whole cell. IHC: human tonsil tissue, human tonsil tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD1b
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene CD1B
Gene Accession No. P29016
Gene Alias Antigen-presenting glycoprotein CD1d2; BDCA1; CD1; CD1.2; CD1A; CD1b; CD1B antigen, b polypeptide; CD1b molecule; CD1C antigen; CD1d.2; Cd1d2; CD1d2 antigen; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; Ly-38; MGC125990; MGC125991; R1; RP11-101J8.3; RP11-101J8.4; T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1d2
Gene Symbols CD1B
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence of human CD1b (DKEVAELEEI FRVYIFGFAR EVQDFAGDFQ MKY).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 910
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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