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CD1C Monoclonal Antibody (OTI5A8), TrueMAB™, OriGene
SDP

Catalog No. 501675880
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30 μL
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50-167-5880 100 μL
50-253-9731 30 μL
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Catalog No. 50-167-5880 Supplier OriGene Supplier No. TA505398
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Description

Mouse Monoclonal Antibody

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

Specifications

Antigen CD1C
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone OTI5A8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene CD1C
Gene Accession No. P29017
Gene Alias BDCA1, CD1, CD1A, R7
Gene Symbols CD1C
Host Species Mouse
Immunogen Full length human recombit protein of human CD1C produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 911
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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