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CD1d Mouse, anti-Rat, R718, Clone: WTH2, BD OptiBuild™

Catalog No. BDB751970 Shop All BD Biosciences Products
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BDB751970 50 μg
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Catalog No. BDB751970 Supplier BD Biosciences Supplier No. 751970
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Description

Mouse Monoclonal Antibody

The WTH2 monoclonal antibody specifically binds to rat CD1d and crossreacts with mouse CD1d. CD1d is a type I transmembrane glycoprotein that is noncovalently associated with β2-microglobulin. CD1d is expressed on various cell types including subsets of thymocytes, T cells, B cells, monocytes, macrophages, dendritic cells, endothelial cells and epithelial cells. Although structurally similar to MHC Class I antigens, CD1d molecules are rather non-polymorphic and serve to present non-peptide antigens such as endogenous or microbial glycolipids to T lymphocytes (NKT cells). The WTH1 monoclonal antibody reportedly binds to a non-overlapping epitope on rat CD1d and also crossreacts with mouse CD1d when compared with WTH2. Both WTH1 and WTH2 reportedly interfere with antigen recognition by CD1d-restricted T cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD1d
Applications Flow Cytometry
Classification Monoclonal
Clone WTH2
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Refrigerate Upon Arrival
Form Liquid
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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