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CD1d1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986237
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50-198-6237 100 μL
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Catalog No. 50-198-6237 Supplier Bioss Supplier No. BS4961R
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Description

Rabbit Polyclonal Antibody

CD1d is a 49 kDa heavy chain associated with Beta 2 microglobulin on cortical thymocytes. Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells. CD1d is the sole group 2 member of the CD1 family of major histocompatibility (MHC) like glycoproteins. The CD1d gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by the CD1d gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease.

Specifications

Antigen CD1d1
Applications Flow Cytometry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CD1D
Gene Accession No. P15813
Gene Alias AI747460; Antigen-presenting glycoprotein CD1d; Antigen-presenting glycoprotein CD1d1; Cd1; Cd1.1; CD1A; CD1D; CD1D antigen; CD1D antigen, d polypeptide; CD1d molecule; CD1d.1; Cd1d1; CD1d1 antigen; CD1d1 molecule; differentiation antigen CD1-alpha-3; HMC class I antigen-like glycoprotein CD1D; Ly-38; R3; R3G1; T-cell surface glycoprotein CD1d; T-cell surface glycoprotein CD1d1; thymocyte antigen CD1D
Gene Symbols CD1D
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from mouse CD1d1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 912
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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