Invitrogen™ CD1e Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563481

Catalog No. PIPA563481

Description

Immunogen sequence: PWSHGNFSKQ ELKNLQSLFQ LYFHSFIRIV QASAGQFQLE YPFEIQILAG CRMNAPQIFL NMAYQGSDF Highest antigen sequence identity to the following orthologs: Mouse - 42%, Rat - 41%.

CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.

Specifications

• Antigen: CD1e
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CD1E
• Gene Alias: CD1A; CD1e; CD1E antigen, e polypeptide; CD1e molecule; differentiation antigen CD1-alpha-3; hCD1e; leukocyte differentiation antigen; R2; R2G1; sCD1e; T-cell surface glycoprotein CD1e, membrane-associated; T-cell surface glycoprotein CD1e, soluble; thymocyte antigen CD1E
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 913
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P15812
• Gene Symbols: CD1E
• Immunogen: Recombinant protein corresponding to Human CD1e. Recombinant protein control fragment (Product #RP-98505).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG