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CD2 Antibody (UMCD2), Alexa Fluor™ 594, Novus Biologicals™
SDP

Catalog No. NP23408A94 Shop All R&D Systems Products
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NP23408A94 0.1 mL
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Catalog No. NP23408A94 Supplier Novus Biologicals Supplier No. NBP234508AF594
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Description

Mouse Monoclonal Antibody

CD2 Monoclonal specifically detects CD2 in Human samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen CD2
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone UMCD2
Conjugate Alexa Fluor 594
Dilution Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CD2 antigen, CD2 antigen (p50), sheep red blood cell receptor, CD2 molecule, Erythrocyte receptor, FLJ46032, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, Rosette receptor, SRBC, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
Gene Symbols CD2
Host Species Mouse
Immunogen Human Thymocytes/Sezary T cells
Purification Method Protein A or G purified
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 914
Test Specificity CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG2a κ
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