CD200 Receptor Mouse anti-Human, Brilliant Violet 421, Clone: OX-108 (also known as OX108), BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 566344

Catalog No. BDB566344

Description

The OX-108 monoclonal antibody specifically binds to CD200R which is also known as OX2 receptor 1 (OX2R) or MOX2 receptor (MOX2R). CD200R is a type I transmembrane glycoprotein that is encoded by CD200R1 (CD200 receptor 1) and belongs to the C2-set domain containing gene family within the Ig superfamily. CD200R functions as an inhibitory receptor when bound by its ligand, CD200. CD200R is expressed by hematopoietic cells including monocytes, macrophages, dendritic cells, Langerhans cells, neutrophils, basophils, most T cells and mast cells. CD200R signaling may regulate the functions of various types of leucocytes.

The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates. BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences. Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates. Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.

Specifications

• Antigen: CD200 Receptor
• Clone: OX-108 (also known as OX108)
• Conjugate: Brilliant Violet 421
• Gene Alias: CD200R1, CD200 receptor 1, hCD200R, CRTR2, HCRTR2, MOX2R, OX2R
• Immunogen: Human CD200R Recombinant Protein
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ