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Invitrogen™ CD200R Monoclonal Antibody (380525)
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Catalog No. PIMA524119
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100 μg
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Catalog No. Quantity
PIMA524119 100 μg
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Catalog No. PIMA524119 Supplier Invitrogen™ Supplier No. MA524119
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Description

Mouse Monoclonal Antibody

In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CD200 R1 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutophils but also by other leucocytes including T-lymphocytes and mast cells. Further mouse studies of a gene related to CD200R suggests that the receptor may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R results in multiple transcript variants. Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD200R
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone 380525
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CD200R1
Gene Accession No. Q8TD46
Gene Alias antigen identified by monoclonal antibody MRC OX-2 receptor; CD200 cell surface glycoprotein receptor; CD200 R1; CD200 receptor 1; CD200R; Cd200r1; Cell surface glycoprotein CD200 receptor 1; cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200; CRTR2; HCRTR2; MOX2 receptor; MOX2R; Orexin receptor 2; OX102 antigen; OX2 receptor; OX2R; UNQ2522/PRO6015
Gene Symbols CD200R1
Host Species Mouse
Immunogen Mouse myeloma cell line NS0-derived recombinant human CD200 R1 Ala27-Leu266 (predicted).
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 131450
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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