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Invitrogen™ CD200R Monoclonal Antibody (OX-110), PE
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Catalog No. MA182713
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100 Tests
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MA182713 100 Tests
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Catalog No. MA182713 Supplier Invitrogen™ Supplier No. MA182713
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Description

Rat Monoclonal Antibody

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Rat anti Mouse CD200R antibody, clone OX-110 recognizes mouse CD200R, a cell surface glycoprotein (also known as OX2R.

CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutophils but also by other leucocytes including T-lymphocytes and mast cells. Further mouse studies of a gene related to CD200R suggests that the receptor may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R results in multiple transcript variants. Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
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Specifications

Antigen CD200R
Applications Flow Cytometry
Classification Monoclonal
Clone OX-110
Concentration Conc. Not Determined
Conjugate PE
Formulation PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene CD200R1
Gene Accession No. Q9ES57
Gene Alias antigen identified by monoclonal antibody MRC OX-2 receptor; CD200 cell surface glycoprotein receptor; CD200 R1; CD200 receptor 1; CD200R; Cd200r1; Cell surface glycoprotein CD200 receptor 1; cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200; CRTR2; HCRTR2; MOX2 receptor; MOX2R; Orexin receptor 2; OX102 antigen; OX2 receptor; OX2R; UNQ2522/PRO6015
Gene Symbols CD200R1
Host Species Rat
Immunogen Fusion protein, mCD200RCD4d3+4.
Purification Method Protein G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57781
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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